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STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the Neurotrophic Factor GDF5
Loss of midbrain dopaminergic (mDA) neurons and their axons is central to Parkinson's disease (PD). Growth differentiation factor (GDF)5 is a potential neurotrophic factor for PD therapy. However, the molecular mediators of its neurotrophic action are unknown. Our proteomics analysis shows that...
Autores principales: | Anantha, Jayanth, Goulding, Susan R., Wyatt, Sean L., Concannon, Ruth M., Collins, Louise M., Sullivan, Aideen M., O'Keeffe, Gerard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452236/ https://www.ncbi.nlm.nih.gov/pubmed/32853992 http://dx.doi.org/10.1016/j.isci.2020.101457 |
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