Cargando…

Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure

Large clinical trials designed to test the efficacy of vagus nerve stimulation (VNS) in patients with heart failure did not demonstrate benefits with respect to the primary endpoints. The nonselective nature of VNS may account for the failure to translate promising results of preclinical and earlier...

Descripción completa

Detalles Bibliográficos
Autores principales: Machhada, Asif, Hosford, Patrick S., Dyson, Alex, Ackland, Gareth L., Mastitskaya, Svetlana, Gourine, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452237/
https://www.ncbi.nlm.nih.gov/pubmed/32875170
http://dx.doi.org/10.1016/j.jacbts.2020.06.002