Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation

In bacteria, the dissociable σ subunit of the RNA polymerase (RNAP) is responsible for initiating RNA synthesis from specific DNA sites. As nascent RNA grows, downstream DNA unwinds and is pulled into the RNAP, causing stress accumulation and initiation complex destabilization. Processive transcript...

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Detalles Bibliográficos
Autores principales: Zuo, Yuhong, De, Swastik, Feng, Yingang, Steitz, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452309/
https://www.ncbi.nlm.nih.gov/pubmed/32829286
http://dx.doi.org/10.1016/j.isci.2020.101445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452309/
https://www.ncbi.nlm.nih.gov/pubmed/32829286
http://dx.doi.org/10.1016/j.isci.2020.101445

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