Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank

BACKGROUND: The three main alleles of the APOE gene (ε4, ε3 and ε2) carry differential risks for conditions including Alzheimer's disease (AD) and cardiovascular disease. Due to their clinical significance, we explored disease associations of the APOE genotypes using a hypothesis-free, data-dri...

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Detalles Bibliográficos
Autores principales: Lumsden, Amanda L., Mulugeta, Anwar, Zhou, Ang, Hyppönen, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452404/
https://www.ncbi.nlm.nih.gov/pubmed/32818802
http://dx.doi.org/10.1016/j.ebiom.2020.102954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452404/
https://www.ncbi.nlm.nih.gov/pubmed/32818802
http://dx.doi.org/10.1016/j.ebiom.2020.102954

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