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Whole-exome mutational landscape of metastasis in patient-derived hepatocellular carcinoma cells

In order to explore the genomic basis for liver cancer metastasis, whole-exome sequencing (WES) was performed on patient-derived hepatocellular carcinoma (HCC) cell lines with differential metastatic potentials and analyzed their clonal evolution relationships. An evolutionary tree based on genomic...

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Detalles Bibliográficos
Autores principales: Zhou, Qian, Li, Zuli, Song, Linlan, Mu, Di, Wang, Jin, Tian, Li, Liao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452411/
https://www.ncbi.nlm.nih.gov/pubmed/32884992
http://dx.doi.org/10.1016/j.gendis.2020.05.003