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HIV-Captured DCs Regulate T Cell Migration and Cell-Cell Contact Dynamics to Enhance Viral Spread

Trafficking of cell-associated HIV-1 from the genital mucosa to lymphoid organs represents a critical first step toward systemic infection. Mature DCs capture and transmit HIV-1 to T cells, but insights into DC-to-T cell viral spread dynamics within a 3-dimensional environment is lacking. Using live...

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Detalles Bibliográficos
Autores principales: Koh, Wan Hon, Lopez, Paul, Ajibola, Oluwaseun, Parvarchian, Roshan, Mohammad, Umar, Hnatiuk, Ryan, Kindrachuk, Jason, Murooka, Thomas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452485/
https://www.ncbi.nlm.nih.gov/pubmed/32798973
http://dx.doi.org/10.1016/j.isci.2020.101427