Cargando…
HIV-Captured DCs Regulate T Cell Migration and Cell-Cell Contact Dynamics to Enhance Viral Spread
Trafficking of cell-associated HIV-1 from the genital mucosa to lymphoid organs represents a critical first step toward systemic infection. Mature DCs capture and transmit HIV-1 to T cells, but insights into DC-to-T cell viral spread dynamics within a 3-dimensional environment is lacking. Using live...
Autores principales: | Koh, Wan Hon, Lopez, Paul, Ajibola, Oluwaseun, Parvarchian, Roshan, Mohammad, Umar, Hnatiuk, Ryan, Kindrachuk, Jason, Murooka, Thomas T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452485/ https://www.ncbi.nlm.nih.gov/pubmed/32798973 http://dx.doi.org/10.1016/j.isci.2020.101427 |
Ejemplares similares
-
Identifying physiological tissue niches that support the HIV reservoir in T cells
por: Ikeogu, Nnamdi, et al.
Publicado: (2023) -
The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration
por: Csaderova, Lucia, et al.
Publicado: (2013) -
HIV-1 trans-Infection Mediated by DCs: The Tip of the Iceberg of Cell-to-Cell Viral Transmission
por: Perez-Zsolt, Daniel, et al.
Publicado: (2021) -
Capturing COVID-19 spread and interplay with multi-hop contact tracing intervention
por: Kim, Jungyeol, et al.
Publicado: (2023) -
Innate sensing of viral infection by pDCs and regulation by IFN-α and HMGB1 of TRAIL expression on pDCs and NK cells
por: Saïdi, Héla, et al.
Publicado: (2014)