Cargando…

Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity

Entada africana is used in non-conventional medicine for the management of liver ailments. A fraction, designated EaF10 (methylene chloride/methanol 90:10, v/v) with promising hepatoprotective activity has been isolated. Since the mechanisms underlying EaF10 hepatoprotective action remain unknown, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kouam, Arnaud Fondjo, Owona, Brice Ayissi, Fifen, Rodrigue, Njayou, Frédéric Nico, Moundipa, Paul Fewou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452572/ https://www.ncbi.nlm.nih.gov/pubmed/32904230 http://dx.doi.org/10.1016/j.heliyon.2020.e04602

Ejemplares similares

Entada africana fraction CH(2)Cl(2)/MEOH 5% inhibits inducible nitric oxide synthase and pro-inflammatory cytokines gene expression induced by lipopolysaccharide in microglia
por: Owona, Brice Ayissi, et al.
Publicado: (2013)

Active chemical fractions of stem bark extract of Khaya grandifoliola C.DC and Entada africana Guill. et Perr. synergistically protect primary rat hepatocytes against paracetamol-induced damage
por: Njayou, Frédéric Nico, et al.
Publicado: (2016)

Hydro-ethanolic extract of Khaya grandifoliola attenuates heavy metals-induced hepato-renal injury in rats by reducing oxidative stress and metals-bioaccumulation
por: Kouam, Arnaud Fondjo, et al.
Publicado: (2022)

Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro
por: Kouam, Arnaud Fondjo, et al.
Publicado: (2021)

The phytochemical and pharmacological actions of Entada africana Guill. & Perr.
por: Yusuf, A.J., et al.
Publicado: (2019)

In silico and in vitro screening of licensed antimalarial drugs for repurposing as inhibitors of hepatitis E virus
por: Tietcheu Galani, Borris Rosnay, et al.
Publicado: (2021)

Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity
por: Kouam, Arnaud F., et al.
Publicado: (2017)

Anti-Inflammatory Potential of Phenolic Compounds Isolated From Entada africana Guill. & Perr. Used in the Republic of Benin
por: Codo Toafode, Nonvignon Murielle, et al.
Publicado: (2022)

Profiling the Antidiabetic Potential of Compounds Identified from Fractionated Extracts of Entada africana toward Glucokinase Stimulation: Computational Insight
por: Onikanni, Sunday Amos, et al.
Publicado: (2023)

Molecular Insight in the Multifunctional Effects of Oridonin
por: Owona, Brice Ayissi, et al.
Publicado: (2015)

The Root Aqueous Extract of Entada africana Guill. et Perr. (Mimosaceae) Inhibits Implant Growth, Alleviates Dysmenorrhea, and Restores Ovarian Dynamic in a Rat Model of Endometriosis
por: Mvondo, Marie Alfrede, et al.
Publicado: (2017)

Protective effect of bixin on carbon tetrachloride-induced hepatotoxicity in rats
por: Moreira, Priscila R, et al.
Publicado: (2014)

Amelioration of Behavioral Impairments and Neuropathology by Antiepileptic Drug Topiramate in a Transgenic Alzheimer’s Disease Model Mice, APP/PS1
por: Owona, Brice Ayissi, et al.
Publicado: (2019)

Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats
por: Feng, Yibin, et al.
Publicado: (2010)

Two New Derivatives of 2, 5-Dihydroxyphenylacetic Acid from the Kernel of Entada phaseoloides
por: Chen, Lin, et al.
Publicado: (2013)

Physical and mechanical properties of Entada mannii particulates reinforced composites
por: Balogun, O.P., et al.
Publicado: (2020)

Effect of seeds of Entada phaseoloides on chronic restrain stress in mice
por: Barua, Chandana Choudhury, et al.
Publicado: (2020)

Role of the Sympathetic Nervous System in Carbon Tetrachloride-Induced Hepatotoxicity and Systemic Inflammation
por: Lin, Jung-Chun, et al.
Publicado: (2015)

Chenopodium album extract ameliorates carbon tetrachloride induced hepatotoxicity in rat model
por: Hussain, Saddam, et al.
Publicado: (2022)

Pharmacological Evaluation of Scopoletin in the Carbon Tetrachloride-Induced Hepatotoxicity Model in Wistar Rats
por: Sharma, Swati, et al.
Publicado: (2022)

Unprecedented Antimicrobial and Cytotoxic Polyketides from Cultures of Diaporthe africana sp. nov.
por: Matio Kemkuignou, Blondelle, et al.
Publicado: (2023)

Hepatoprotective activity of Leptadenia reticulata stems against carbon tetrachloride-induced hepatotoxicity in rats
por: Nema, Amit Kumar, et al.
Publicado: (2011)

PROTECTIVE EFFECT OF FRACTION OF AZADIRACHTA INDICA LEAF EXTRACT ON CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY
por: Mukherjee, Pulok K., et al.
Publicado: (1994)

Hepatoprotective effect of Stachys pilifera ethanol extract in carbon tetrachloride-induce hepatotoxicity in rats
por: Panahi Kokhdan, Esmaeel, et al.
Publicado: (2017)

Hepatoprotective effects of Berberis vulgaris leaf extract on carbon tetrachloride-induced hepatotoxicity in rats
por: Tahmasebi, Maryam, et al.
Publicado: (2018)

Weaning Mice and Adult Mice Exhibit Differential Carbon Tetrachloride-Induced Acute Hepatotoxicity
por: Jeong, Tae Bin, et al.
Publicado: (2020)

Activation of Nrf2 Protects against Triptolide-Induced Hepatotoxicity
por: Li, Jia, et al.
Publicado: (2014)

Recent Updates on Acetaminophen Hepatotoxicity: The Role of Nrf2 in Hepatoprotection
por: Gum, Sang Il, et al.
Publicado: (2013)

Escultura africana ; Artesanía africana

Plant extracts from Cameroonian medicinal plants strongly inhibit hepatitis C virus infection in vitro
por: Galani, Borris R. T., et al.
Publicado: (2015)

Protection against carbon tetrachloride-induced hepatotoxicity by pretreating rats with the hemisuccinate esters of tocopherol and cholesterol.
por: Fariss, M W, et al.
Publicado: (1993)

Hydrogen Sulfide Attenuates Carbon Tetrachloride-Induced Hepatotoxicity, Liver Cirrhosis and Portal Hypertension in Rats
por: Tan, Gang, et al.
Publicado: (2011)

ANTIHEPATOTOXIC EFFECT OF MARRUBIUM VULGARE AND WITHANIA SOMNIFERA EXTRACTS ON CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS
por: Elberry, Ahmed A., et al.
Publicado: (2010)

Antioxidant and hepatoprotective effects of flower extract of Millingtonia hortensis Linn. on carbon tetrachloride induced hepatotoxicity
por: Babitha, S., et al.
Publicado: (2012)

Hepatoprotective effect of Rosa canina fruit extract against carbon tetrachloride induced hepatotoxicity in rat
por: Sadeghi, Heibatollah, et al.
Publicado: (2016)

Amelioration of carbon tetrachloride induced hepatotoxicity in rats by standardized Feronia limonia. Linn leaf extracts
por: Jain, Mahendra, et al.
Publicado: (2012)

Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice
por: Lu, Yuan-Fu, et al.
Publicado: (2014)

Orestiada Africana
Publicado: (1989)

Risa Africana/
por: Lessing, Doris, 1919-2013

Colchicine antimitosis abolishes resiliency of postnatally developing rats to chlordecone-amplified carbon tetrachloride hepatotoxicity and lethality.
por: Dalu, A, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_ple8m5u7hqbdjrtsgvk7v8r4vo