BxPC-3-Derived Small Extracellular Vesicles Induce FOXP3+ Treg through ATM-AMPK-Sirtuins-Mediated FOXOs Nuclear Translocations

Immunotherapy in pancreatic ductal adenocarcinoma (PDAC) treatment faces serious challenges, due particularly to the poor immunogenicity. Cancer cell-derived small extracellular vesicles (sEVs) play important roles in damaging the immune system. However, the effects of pancreatic cancer-derived sEVs...

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Detalles Bibliográficos
Autores principales: Shen, Tao, Jia, Shengnan, Ding, Guoping, Ping, Dongnan, Zhou, Liangjing, Zhou, Senhao, Cao, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452591/
https://www.ncbi.nlm.nih.gov/pubmed/32798974
http://dx.doi.org/10.1016/j.isci.2020.101431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452591/
https://www.ncbi.nlm.nih.gov/pubmed/32798974
http://dx.doi.org/10.1016/j.isci.2020.101431

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