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N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1

BACKGROUND: Metastasis is the leading cause of death in patients with osteosarcoma. Some of these patients fail to respond to chemotherapy and die of metastasis within a short period. Therefore, it is important to identify novel biomarkers to improve the diagnosis and treatment of osteosarcoma. TRIM...

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Detalles Bibliográficos
Autores principales: Zhou, Chenliang, Zhang, Zhichang, Zhu, Xiaoshi, Qian, Guowei, Zhou, Yan, Sun, Yong, Yu, Wenxi, Wang, Jiahui, Lu, Haiyang, Lin, Feng, Shen, Zan, Zheng, Shuier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452680/
https://www.ncbi.nlm.nih.gov/pubmed/32853985
http://dx.doi.org/10.1016/j.ebiom.2020.102955