Barium blockade of the KcsA channel in open and closed conformation datasets

Barium is a potent blocker of the KcsA potassium channel. A strategy using x-ray crystallography and molecular dynamics (MD) simulation has been used to understand this phenomenon as described in Rohaim et al. [1]. Wild type KcsA is purified to homogeneity and crystallized in low and high K(+) condi...

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Detalles Bibliográficos
Autores principales: Rohaim, Ahmed, Gong, LiDong, Li, Jing, Rui, Huan, Blachowicz, Lydia, Roux, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452694/
https://www.ncbi.nlm.nih.gov/pubmed/32904340
http://dx.doi.org/10.1016/j.dib.2020.106135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452694/
https://www.ncbi.nlm.nih.gov/pubmed/32904340
http://dx.doi.org/10.1016/j.dib.2020.106135

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