Hypermethylation status of DAPK, MGMT and RUNX3 in HPV negative oral and oropharyngeal squamous cell carcinoma

Squamous cell carcinoma of the oral cavity and oropharynx is the sixth most common type of cancer in the world. During tumorigenesis, gene promoter hypermethylation is considered an important mechanism of transcription silencing of tumor suppressor genes, such as DAPK, MGMT and RUNX3. These genes pa...

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Detalles Bibliográficos
Autores principales: dos Reis, Raquel Silva, dos Santos, Jéssica Aflávio, de Abreu, Priscila Marinho, Dettogni, Raquel Spinassé, dos Santos, Eldamária de Vargas Wolfgramm, Stur, Elaine, Agostini, Lidiane Pignaton, Anders, Quézia Silva, Alves, Lyvia Neves Rebello, do Valle, Isabella Bittencourt, Lima, Marília Arantes, Souza, Evandro Duccini, de Podestá, José Roberto Vasconcelos, von Zeidler, Sandra Ventorin, Cordeiro-Silva, Melissa de Freitas, Louro, Iúri Drumond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452731/
https://www.ncbi.nlm.nih.gov/pubmed/32870234
http://dx.doi.org/10.1590/1678-4685-GMB-2019-0334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452731/
https://www.ncbi.nlm.nih.gov/pubmed/32870234
http://dx.doi.org/10.1590/1678-4685-GMB-2019-0334

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