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Optogenetic Stimulation of Cholinergic Amacrine Cells Improves Capillary Blood Flow in Diabetic Retinopathy

PURPOSE: Disruption in blood supply to active retinal circuits is the earliest hallmark of diabetic retinopathy (DR) and has been primarily attributed to vascular deficiency. However, accumulating evidence supports an early role for a disrupted neuronal function in blood flow impairment. Here, we te...

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Detalles Bibliográficos
Autores principales: Ivanova, Elena, Bianchimano, Paola, Corona, Carlo, Eleftheriou, Cyril G., Sagdullaev, Botir T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452855/
https://www.ncbi.nlm.nih.gov/pubmed/32841313
http://dx.doi.org/10.1167/iovs.61.10.44