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Endogenous toxic metabolites and implications in cancer therapy

It is well recognized that many metabolic enzymes play essential roles in cancer cells in producing building blocks such as nucleotides, which are required in greater amounts due to their increased proliferation. On the other hand, the significance of enzymes in preventing the accumulation of their...

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Detalles Bibliográficos
Autores principales: Lee, Namgyu, Spears, Meghan E., Carlisle, Anne E., Kim, Dohoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452860/
https://www.ncbi.nlm.nih.gov/pubmed/32709924
http://dx.doi.org/10.1038/s41388-020-01395-9