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Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression

BACKGROUND: Recent studies have shown that traditional serrated adenoma (TSA) can be classified into BRAF and KRAS subtypes. Here, we examined the clinicopathological and molecular findings of 73 TSAs. MATERIALS AND METHODS: TSAs were subclassified into BRAF type (46 cases, type A) and KRAS type (27...

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Detalles Bibliográficos
Autores principales: Tanaka, Yoshihito, Eizuka, Makoto, Uesugi, Noriyuki, Kawasaki, Keisuke, Yamano, Hiroo, Suzuki, Hiromu, Matsumoto, Takayuki, Sugai, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452875/
https://www.ncbi.nlm.nih.gov/pubmed/32535664
http://dx.doi.org/10.1007/s00535-020-01697-5