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Investigation of Potential Drug–Drug Interactions between Peficitinib (ASP015K) and Methotrexate in Patients with Rheumatoid Arthritis

BACKGROUND: Methotrexate is frequently used to treat rheumatoid arthritis. Peficitinib (ASP015K; Smyraf(®)), an oral Janus kinase inhibitor indicated for the treatment of rheumatoid arthritis, may be coadministered with methotrexate. OBJECTIVE: The objective of this study was to investigate potentia...

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Detalles Bibliográficos
Autores principales: Zhu, Tong, Moy, Selina, Valluri, Udaya, Cao, Ying, Zhang, Wenhui, Sawamoto, Taiji, Chindalore, Vishala, Akinlade, Bola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452880/
https://www.ncbi.nlm.nih.gov/pubmed/32591978
http://dx.doi.org/10.1007/s40261-020-00937-z