Ribosome-mediated polymerization of long chain carbon and cyclic amino acids into peptides in vitro

Ribosome-mediated polymerization of backbone-extended monomers into polypeptides is challenging due to their poor compatibility with the translation apparatus, which evolved to use α-L-amino acids. Moreover, mechanisms to acylate (or charge) these monomers to transfer RNAs (tRNAs) to make aminoacyl-...

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Detalles Bibliográficos
Autores principales: Lee, Joongoo, Schwarz, Kevin J., Kim, Do Soon, Moore, Jeffrey S., Jewett, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452890/
https://www.ncbi.nlm.nih.gov/pubmed/32855412
http://dx.doi.org/10.1038/s41467-020-18001-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452890/
https://www.ncbi.nlm.nih.gov/pubmed/32855412
http://dx.doi.org/10.1038/s41467-020-18001-x

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