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In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors
The high mortality rate from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in humans and the lack of effective therapeutic regime for its treatment necessitates the identification of new antivirals. SARS-CoV-2 relies on non-structural proteins such as Nsp13 helicase and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452913/ https://www.ncbi.nlm.nih.gov/pubmed/32875166 http://dx.doi.org/10.1016/j.genrep.2020.100860 |