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Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis

Visceral organs, such as the lungs, stomach and liver, are derived from the fetal foregut through a series of inductive interactions between the definitive endoderm (DE) and the surrounding splanchnic mesoderm (SM). While DE patterning is fairly well studied, the paracrine signaling controlling SM r...

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Detalles Bibliográficos
Autores principales: Han, Lu, Chaturvedi, Praneet, Kishimoto, Keishi, Koike, Hiroyuki, Nasr, Talia, Iwasawa, Kentaro, Giesbrecht, Kirsten, Witcher, Phillip C., Eicher, Alexandra, Haines, Lauren, Lee, Yarim, Shannon, John M., Morimoto, Mitsuru, Wells, James M., Takebe, Takanori, Zorn, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453027/
https://www.ncbi.nlm.nih.gov/pubmed/32855417
http://dx.doi.org/10.1038/s41467-020-17968-x