Comparative Population Pharmacokinetics of Darunavir in SARS-CoV-2 Patients vs. HIV Patients: The Role of Interleukin-6

BACKGROUND: Darunavir is an anti-HIV protease inhibitor repurposed for SARS-CoV-2 treatment. OBJECTIVE: The aim of this study was to assess the population pharmacokinetics of darunavir in SARS-CoV-2 patients compared with HIV patients. METHODS: Two separate models were created by means of a nonlinea...

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Detalles Bibliográficos
Autores principales: Cojutti, Pier Giorgio, Londero, Angela, Della Siega, Paola, Givone, Filippo, Fabris, Martina, Biasizzo, Jessica, Tascini, Carlo, Pea, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453069/
https://www.ncbi.nlm.nih.gov/pubmed/32856282
http://dx.doi.org/10.1007/s40262-020-00933-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453069/
https://www.ncbi.nlm.nih.gov/pubmed/32856282
http://dx.doi.org/10.1007/s40262-020-00933-8

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