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Comparative Population Pharmacokinetics of Darunavir in SARS-CoV-2 Patients vs. HIV Patients: The Role of Interleukin-6

BACKGROUND: Darunavir is an anti-HIV protease inhibitor repurposed for SARS-CoV-2 treatment. OBJECTIVE: The aim of this study was to assess the population pharmacokinetics of darunavir in SARS-CoV-2 patients compared with HIV patients. METHODS: Two separate models were created by means of a nonlinea...

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Detalles Bibliográficos
Autores principales:	Cojutti, Pier Giorgio, Londero, Angela, Della Siega, Paola, Givone, Filippo, Fabris, Martina, Biasizzo, Jessica, Tascini, Carlo, Pea, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453069/ https://www.ncbi.nlm.nih.gov/pubmed/32856282 http://dx.doi.org/10.1007/s40262-020-00933-8

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