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Nrp-1 Mediated Plasmatic Ago2 Binding miR-21a-3p Internalization: A Novel Mechanism for miR-21a-3p Accumulation in Renal Tubular Epithelial Cells during Sepsis

The mechanism underlying sepsis-associated acute kidney injury (SAKI), which is an independent risk factor for sepsis-associated death, is unclear. A previous study indicates that during sepsis miR-21a-3p accumulates in renal tubular epithelial cells (TECs) as the mediator of inflammation and mediat...

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Detalles Bibliográficos
Autores principales: Zou, Zhiqiang, Lin, Qin, Yang, Huobao, Liu, Zhongwei, Zheng, Shixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453242/
https://www.ncbi.nlm.nih.gov/pubmed/32923478
http://dx.doi.org/10.1155/2020/2370253