Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose

BACKGROUND: The Plasmodium falciparum sexual-stage surface proteins Pfs25 and Pfs230 are antigen candidates for a malaria transmission-blocking vaccine (TBV), and have been widely investigated as such. It is not clear whether simultaneously presenting these two antigens in a particulate vaccine woul...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Chiao, Deng, Bingbing, Mabrouk, Moustafa T., Seffouh, Amal, Ortega, Joaquin, Long, Carole, Miura, Kazutoyo, Wu, Yimin, Lovell, Jonathan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453371/
https://www.ncbi.nlm.nih.gov/pubmed/32859199
http://dx.doi.org/10.1186/s12936-020-03368-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453371/
https://www.ncbi.nlm.nih.gov/pubmed/32859199
http://dx.doi.org/10.1186/s12936-020-03368-5

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