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Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose
BACKGROUND: The Plasmodium falciparum sexual-stage surface proteins Pfs25 and Pfs230 are antigen candidates for a malaria transmission-blocking vaccine (TBV), and have been widely investigated as such. It is not clear whether simultaneously presenting these two antigens in a particulate vaccine woul...
Autores principales: | Huang, Wei-Chiao, Deng, Bingbing, Mabrouk, Moustafa T., Seffouh, Amal, Ortega, Joaquin, Long, Carole, Miura, Kazutoyo, Wu, Yimin, Lovell, Jonathan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453371/ https://www.ncbi.nlm.nih.gov/pubmed/32859199 http://dx.doi.org/10.1186/s12936-020-03368-5 |
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