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Probing the unfolded protein response in long-lived naked mole-rats

The long-living naked mole-rat (NMR) shows negligible senescence and resistance to age-associated diseases. Recent evidence, based on protein-level assays, suggests that enhanced protein homeostasis machinery contributes to NMR stress-resistance and longevity. Here, we develop NMR-specific, transcri...

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Detalles Bibliográficos
Autores principales: Du, Zhen, Chakrabarti, Sampurna, Kulaberoglu, Yavuz, Smith, Ewan St John, Dobson, Christopher M., Itzhaki, Laura S., Kumita, Janet R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453385/
https://www.ncbi.nlm.nih.gov/pubmed/32819579
http://dx.doi.org/10.1016/j.bbrc.2020.06.118