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Effect of pre-freezing and saccharide types in freeze-drying of siRNA lipoplexes on gene-silencing effects in the cells by reverse transfection

Our previous study reported that reverse (Rev)-transfection with small interfering RNA (siRNA)/cationic liposome complexes (siRNA lipoplexes) freeze-dried in trehalose or sucrose solution resulted in high gene-silencing activity in cells. The current study investigated whether pre-freezing or saccha...

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Detalles Bibliográficos
Autores principales: Tang, Min, Hu, Subin, Hattori, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453497/
https://www.ncbi.nlm.nih.gov/pubmed/32945442
http://dx.doi.org/10.3892/mmr.2020.11419