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Phosphorylation of STAT3 and ERBB2 mediates hypoxia-induced VEGF release in ARPE-19 cells

Neovascularization in the retina can cause loss of vision. Vascular endothelial growth factor (VEGF) serves an important role in the pathogenesis of retinal vascular diseases. Hypoxia is a notable cause of VEGF release and both STAT3 and ERBB2 are known to be associated with VEGF. In addition, STAT3...

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Detalles Bibliográficos
Autores principales: Hwang, Soohyun, Seong, Hyemin, Ryu, Jinhyun, Jeong, Joo Yeon, Kang, Tae Seen, Nam, Ki Yup, Seo, Seong Wook, Kim, Seong Jae, Kang, Sang Soo, Han, Yong Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453508/
https://www.ncbi.nlm.nih.gov/pubmed/32945388
http://dx.doi.org/10.3892/mmr.2020.11344