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Intranasal administration of Cytoglobin modifies human umbilical cord-derived mesenchymal stem cells and improves hypoxic-ischemia brain damage in neonatal rats by modulating p38 MAPK signaling-mediated apoptosis

Neonatal hypoxic-ischemic brain damage (HIBD) is a common clinical syndrome in newborns. Hypothermia is the only approved therapy for the clinical treatment; however, the therapeutic window of hypothermia is confined to 6 h after birth and even then, >40% of the infants either die or survive with...

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Detalles Bibliográficos
Autores principales: Yang, Hanhua, Tian, Shufeng, Xie, Lichun, Chen, Yunbin, Ma, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453519/
https://www.ncbi.nlm.nih.gov/pubmed/32945464
http://dx.doi.org/10.3892/mmr.2020.11436