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Intranasal administration of Cytoglobin modifies human umbilical cord-derived mesenchymal stem cells and improves hypoxic-ischemia brain damage in neonatal rats by modulating p38 MAPK signaling-mediated apoptosis
Neonatal hypoxic-ischemic brain damage (HIBD) is a common clinical syndrome in newborns. Hypothermia is the only approved therapy for the clinical treatment; however, the therapeutic window of hypothermia is confined to 6 h after birth and even then, >40% of the infants either die or survive with...
Autores principales: | Yang, Hanhua, Tian, Shufeng, Xie, Lichun, Chen, Yunbin, Ma, Lian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453519/ https://www.ncbi.nlm.nih.gov/pubmed/32945464 http://dx.doi.org/10.3892/mmr.2020.11436 |
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