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Effect of selective inhibition or activation of PGE2 EP1 receptor on glomerulosclerosis

Prostaglandin E2 (PGE2) is involved in numerous physiological and pathological processes of the kidney via its four receptors. A previous study has suggested that a defect in the PGE2 receptor 1 (EP1) gene markedly suppressed the transforming growth factor-β1 (TGF-β1)-induced mesangial cell (MC) pro...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Yin, Jun, Xu, Yuyin, Qiu, Zhi, Liu, Jing, Chen, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453572/
https://www.ncbi.nlm.nih.gov/pubmed/32700746
http://dx.doi.org/10.3892/mmr.2020.11353