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Paired-related homeobox 1 overexpression promotes multidrug resistance via PTEN/PI3K/AKT signaling in MCF-7 breast cancer cells

Multidrug resistance (MDR) is a major cause of disease relapse and mortality in breast cancer. Paired-related homeobox 1 (PRRX1) is associated with the epithelial-mesenchymal transition (EMT), which is involved in tumor development, including cell invasion and MDR. However, the effect of PRRX1 on MD...

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Detalles Bibliográficos
Autores principales: Luo, Haoyue, Cong, Shaobo, Dong, Jiaojiao, Jin, Litao, Jiang, Dandan, Wang, Xingang, Chen, Qingfeng, Li, Funian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453582/
https://www.ncbi.nlm.nih.gov/pubmed/32945446
http://dx.doi.org/10.3892/mmr.2020.11414