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Paired-related homeobox 1 overexpression promotes multidrug resistance via PTEN/PI3K/AKT signaling in MCF-7 breast cancer cells
Multidrug resistance (MDR) is a major cause of disease relapse and mortality in breast cancer. Paired-related homeobox 1 (PRRX1) is associated with the epithelial-mesenchymal transition (EMT), which is involved in tumor development, including cell invasion and MDR. However, the effect of PRRX1 on MD...
Autores principales: | Luo, Haoyue, Cong, Shaobo, Dong, Jiaojiao, Jin, Litao, Jiang, Dandan, Wang, Xingang, Chen, Qingfeng, Li, Funian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453582/ https://www.ncbi.nlm.nih.gov/pubmed/32945446 http://dx.doi.org/10.3892/mmr.2020.11414 |
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