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Inhibition of HtrA2 alleviates inflammatory response and cell apoptosis in lipopolysaccharide-induced acute pneumonia in rats

Pneumonia is one of the commonest causes of death worldwide. High-temperature requirement A2 (HtrA2) is a proapoptotic mitochondrial serine protease involved in caspase-dependent or caspase-independent cell apoptosis. UCF-101 (5-[5-(2-nitrophenyl) furfuryl iodine]-1,3-diphenyl-2-thiobarbituric acid)...

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Detalles Bibliográficos
Autor principal: Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453584/
https://www.ncbi.nlm.nih.gov/pubmed/32945404
http://dx.doi.org/10.3892/mmr.2020.11410