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Metformin promotes cell proliferation and osteogenesis under high glucose condition by regulating the ROS-AKT-mTOR axis

Metformin, a cost-effective and safe orally administered antidiabetic drug used by millions of patients, has exhibited great interest for its potential osteogenic-promoting properties in different types of cells, including mesenchymal stem cells (MSCs). Diabetic osteopathy is a common comorbidity of...

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Detalles Bibliográficos
Autores principales: Zhou, Renyi, Ma, Yue, Qiu, Shui, Gong, Zunlei, Zhou, Xiaoshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453594/
https://www.ncbi.nlm.nih.gov/pubmed/32945402
http://dx.doi.org/10.3892/mmr.2020.11391