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Role of the HIF-1α/SDF-1/CXCR4 signaling axis in accelerated fracture healing after craniocerebral injury

The hypoxic state of the brain tissue surrounding craniocerebral injury induces an increase in the secretion of HIF-1α during the healing process. HIF-1α can promote mesenchymal stem cell (MSC) migration to ischemic and hypoxic sites by regulating the expression levels of molecules such as stromal c...

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Detalles Bibliográficos
Autores principales: Xue, Yonghua, Li, Zhikun, Wang, Yi, Zhu, Xiaodong, Hu, Ruixi, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453606/
https://www.ncbi.nlm.nih.gov/pubmed/32945380
http://dx.doi.org/10.3892/mmr.2020.11361