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Therapeutic Effects of Fibroblast Growth Factor-21 on Diabetic Nephropathy and the Possible Mechanism in Type 1 Diabetes Mellitus Mice

BACKGROUND: Fibroblast growth factor 21 (FGF21) has been only reported to prevent type 1 diabetic nephropathy (DN) in the streptozotocin-induced type 1 diabetes mellitus (T1DM) mouse model. However, the FVB (Cg)-Tg (Cryaa-Tag, Ins2-CALM1) 26OVE/PneJ (OVE26) transgenic mouse is a widely recommended m...

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Detalles Bibliográficos
Autores principales: Weng, Wenya, Ge, Tingwen, Wang, Yi, He, Lulu, Liu, Tinghao, Wang, Wanning, Zheng, Zongyu, Yu, Lechu, Zhang, Chi, Lu, Xuemian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453991/
https://www.ncbi.nlm.nih.gov/pubmed/32431116
http://dx.doi.org/10.4093/dmj.2019.0089