Complement inhibitor factor H expressed by breast cancer cells differentiates CD14(+) human monocytes into immunosuppressive macrophages

Macrophages are a major immune cell type in the tumor microenvironment, where they display a tumor-supporting phenotype. Factor H (FH) is a complement inhibitor that also plays a role in several cellular functions. To date, the phenotype of monocytes stimulated with FH has been unexplored. We discov...

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Detalles Bibliográficos
Autores principales: Smolag, Karolina I., Mueni, Christine M., Leandersson, Karin, Jirström, Karin, Hagerling, Catharina, Mörgelin, Matthias, Barlow, Paul N., Martin, Myriam, Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453999/
https://www.ncbi.nlm.nih.gov/pubmed/32923173
http://dx.doi.org/10.1080/2162402X.2020.1731135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453999/
https://www.ncbi.nlm.nih.gov/pubmed/32923173
http://dx.doi.org/10.1080/2162402X.2020.1731135

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