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Complement inhibitor factor H expressed by breast cancer cells differentiates CD14(+) human monocytes into immunosuppressive macrophages

Macrophages are a major immune cell type in the tumor microenvironment, where they display a tumor-supporting phenotype. Factor H (FH) is a complement inhibitor that also plays a role in several cellular functions. To date, the phenotype of monocytes stimulated with FH has been unexplored. We discov...

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Detalles Bibliográficos
Autores principales:	Smolag, Karolina I., Mueni, Christine M., Leandersson, Karin, Jirström, Karin, Hagerling, Catharina, Mörgelin, Matthias, Barlow, Paul N., Martin, Myriam, Blom, Anna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453999/ https://www.ncbi.nlm.nih.gov/pubmed/32923173 http://dx.doi.org/10.1080/2162402X.2020.1731135

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