Cargando…

fosA3 overexpression with transporter mutations mediates high-level of fosfomycin resistance and silence of fosA3 in fosfomycin-susceptible Klebsiella pneumoniae producing carbapenemase clinical isolates

The effective treatment of carbapenemase-producing Klebsiella pneumoniae infection has been limited and required novel potential agents. Due to the novel drug development crisis, using old antimicrobial agents and combination therapy have been highlighted. This study focused on fosfomycin which inhi...

Descripción completa

Detalles Bibliográficos
Autores principales: Singkham-in, Uthaibhorn, Muhummudaree, Netchanok, Chatsuwan, Tanittha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454978/
https://www.ncbi.nlm.nih.gov/pubmed/32857767
http://dx.doi.org/10.1371/journal.pone.0237474