Cargando…

Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages

Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate phagocytic cells to destroy ingested Cn is strongly influenced by polarization state with classically (M1) activated macropha...

Descripción completa

Detalles Bibliográficos
Autores principales: Subramani, Aarthi, Griggs, Prianca, Frantzen, Niah, Mendez, James, Tucker, Jamila, Murriel, Jada, Sircy, Linda M., Millican, Grace E., McClelland, Erin E., Seipelt-Thiemann, Rebecca L., Nelson, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454990/
https://www.ncbi.nlm.nih.gov/pubmed/32857777
http://dx.doi.org/10.1371/journal.pone.0233818