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Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages
Macrophages serve as a first line of defense against infection with the facultative intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate phagocytic cells to destroy ingested Cn is strongly influenced by polarization state with classically (M1) activated macropha...
Autores principales: | Subramani, Aarthi, Griggs, Prianca, Frantzen, Niah, Mendez, James, Tucker, Jamila, Murriel, Jada, Sircy, Linda M., Millican, Grace E., McClelland, Erin E., Seipelt-Thiemann, Rebecca L., Nelson, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454990/ https://www.ncbi.nlm.nih.gov/pubmed/32857777 http://dx.doi.org/10.1371/journal.pone.0233818 |
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