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Mathematical modelling reveals cellular dynamics within tumour spheroids

Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutrients and oxygen from the surrounding culture mediu...

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Detalles Bibliográficos
Autores principales: Bull, Joshua A., Mech, Franziska, Quaiser, Tom, Waters, Sarah L., Byrne, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455028/
https://www.ncbi.nlm.nih.gov/pubmed/32810174
http://dx.doi.org/10.1371/journal.pcbi.1007961