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Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration

Epidermal lineages and injury induced regeneration are controlled by transcriptional programs coordinating cellular signaling and epigenetic regulators, but the mechanism remains unclear. Previous studies showed that conditional deletion of the transcriptional coactivator Mediator 1 (Med1) changes e...

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Detalles Bibliográficos
Autores principales: Oda, Yuko, Nguyen, Thai, Hata, Akiko, Meyer, Mark B., Pike, J. Wesley, Bikle, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455038/
https://www.ncbi.nlm.nih.gov/pubmed/32857768
http://dx.doi.org/10.1371/journal.pone.0238076