Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

Targeting a universal host protein exploited by most viruses would be a game-changing strategy that offers broad-spectrum solution and rapid pandemic control including the current COVID-19. Here, we found a common YxxØ-motif of multiple viruses that exploits host AP2M1 for intracellular trafficking....

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Detalles Bibliográficos
Autores principales: Yuan, Shuofeng, Chu, Hin, Huang, Jingjing, Zhao, Xiaoyu, Ye, Zi-Wei, Lai, Pok-Man, Wen, Lei, Cai, Jian-Piao, Mo, Yufei, Cao, Jianli, Liang, Ronghui, Poon, Vincent Kwok-Man, Sze, Kong-Hung, Zhou, Jie, To, Kelvin Kai-Wang, Chen, Zhiwei, Chen, Honglin, Jin, Dong-Yan, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455044/
https://www.ncbi.nlm.nih.gov/pubmed/32923629
http://dx.doi.org/10.1126/sciadv.aba7910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455044/
https://www.ncbi.nlm.nih.gov/pubmed/32923629
http://dx.doi.org/10.1126/sciadv.aba7910

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