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Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production

Evidence has mounted that insulin can be synthesized in various brain regions, including the hypothalamus. However, the distribution and functions of insulin-expressing cells in the hypothalamus remain elusive. Herein, we show that in the mouse hypothalamus, the perikarya of insulin-positive neurons...

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Detalles Bibliográficos
Autores principales: Lee, Jaemeun, Kim, Kyungchan, Cho, Jae Hyun, Bae, Jin Young, O’Leary, Timothy P., Johnson, James D., Bae, Yong Chul, Kim, Eun-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455129/
https://www.ncbi.nlm.nih.gov/pubmed/32644973
http://dx.doi.org/10.1172/jci.insight.135412