Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease

Airway mucociliary clearance (MCC) is the main mechanism of lung defense keeping airways free of infection and mucus obstruction. Airway surface liquid volume, ciliary beating, and mucus are central for proper MCC and critically regulated by sodium absorption and anion secretion. Impaired MCC is a k...

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Detalles Bibliográficos
Autores principales: Vega, Génesis, Guequén, Anita, Philp, Amber R., Gianotti, Ambra, Arzola, Llilian, Villalón, Manuel, Zegarra-Moran, Olga, Galietta, Luis J.V., Mall, Marcus A., Flores, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455130/
https://www.ncbi.nlm.nih.gov/pubmed/32814712
http://dx.doi.org/10.1172/jci.insight.140076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455130/
https://www.ncbi.nlm.nih.gov/pubmed/32814712
http://dx.doi.org/10.1172/jci.insight.140076

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