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Lipid mediators and biomarkers associated with type 1 diabetes development

Type 1 diabetes (T1D) is a consequence of autoimmune β cell destruction, but the role of lipids in this process is unknown. We previously reported that activation of Ca(2+)-independent phospholipase A(2)β (iPLA(2)β) modulates polarization of macrophages (MΦ). Hydrolysis of the sn-2 substituent of gl...

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Detalles Bibliográficos
Autores principales: Nelson, Alexander J., Stephenson, Daniel J., Bone, Robert N., Cardona, Christopher L., Park, Margaret A., Tusing, Ying G., Lei, Xiaoyong, Kokotos, George, Graves, Christina L., Mathews, Clayton E., Kramer, Joanna, Hessner, Martin J., Chalfant, Charles E., Ramanadham, Sasanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455134/
https://www.ncbi.nlm.nih.gov/pubmed/32814707
http://dx.doi.org/10.1172/jci.insight.138034