Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target

Granulosa cell tumors (GCT) are rare ovarian malignancies. Due to the lack of effective treatment in late relapse, there is a clear unmet need for novel therapies. Forkhead Box L2 (FOXL2) is a protein mainly expressed in granulosa cells (GC) and therefore is a rational therapeutic target. Since we i...

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Detalles Bibliográficos
Autores principales: Pierini, Stefano, Tanyi, Janos L., Simpkins, Fiona, George, Erin, Uribe-Herranz, Mireia, Drapkin, Ronny, Burger, Robert, Morgan, Mark A., Facciabene, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455139/
https://www.ncbi.nlm.nih.gov/pubmed/32814714
http://dx.doi.org/10.1172/jci.insight.136773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455139/
https://www.ncbi.nlm.nih.gov/pubmed/32814714
http://dx.doi.org/10.1172/jci.insight.136773

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