Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

Overuse injuries to dense collagenous tissues are common, but their etiology is poorly understood. The predominant hypothesis that micro-damage accumulation exceeds the rate of biological repair is missing a mechanistic explanation. Here, we used collagen hybridizing peptides to measure collagen mol...

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Detalles Bibliográficos
Autores principales: Zitnay, Jared L., Jung, Gang Seob, Lin, Allen H., Qin, Zhao, Li, Yang, Yu, S. Michael, Buehler, Markus J., Weiss, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455178/
https://www.ncbi.nlm.nih.gov/pubmed/32923623
http://dx.doi.org/10.1126/sciadv.aba2795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455178/
https://www.ncbi.nlm.nih.gov/pubmed/32923623
http://dx.doi.org/10.1126/sciadv.aba2795

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