Cargando…
Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues
Overuse injuries to dense collagenous tissues are common, but their etiology is poorly understood. The predominant hypothesis that micro-damage accumulation exceeds the rate of biological repair is missing a mechanistic explanation. Here, we used collagen hybridizing peptides to measure collagen mol...
Autores principales: | Zitnay, Jared L., Jung, Gang Seob, Lin, Allen H., Qin, Zhao, Li, Yang, Yu, S. Michael, Buehler, Markus J., Weiss, Jeffrey A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455178/ https://www.ncbi.nlm.nih.gov/pubmed/32923623 http://dx.doi.org/10.1126/sciadv.aba2795 |
Ejemplares similares
-
Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
por: Zitnay, Jared L., et al.
Publicado: (2017) -
Cyclic Peptide
Mimetic of Damaged Collagen
por: Ellison, Aubrey J., et al.
Publicado: (2020) -
Molecular origin of viscoelasticity in mineralized collagen fibrils
por: Milazzo, Mario, et al.
Publicado: (2021) -
Modelling The Combined Effects Of Collagen and Cyclic Strain On Cellular Orientation In Collagenous Tissues
por: Ristori, T., et al.
Publicado: (2018) -
Large Deformation Mechanisms, Plasticity, and Failure of an Individual Collagen Fibril With Different Mineral Content
por: Depalle, Baptiste, et al.
Publicado: (2016)